物理治疗方法在长期COVID中持续性呼吸不良的有效性:系统性审查和元分析
Christophe Romanet1, Johan Wormser1, Marine Cachanado2
1Department of Intensive Care, Groupe Hospitalier Paris Saint Joseph, Paris, France.
Respiratory medicine
|December 12, 2024
概括
长期COVID幸存者患有持续性呼吸障碍可能受益于物理治疗. 高强度肺部康复在缓解呼吸道症状方面显示出显著的有效性,尽管需要更一致的方法.
科学领域:
- 医疗康复 医疗康复
- 肺部病理学 肺部病理学
- 传染病 传染病 传染病
背景情况:
- 持续性呼吸不良是COVID-19的常见长期症状,严重影响生活质量和心理健康.
- 长期COVID建议使用物理治疗,但其有效性的证据仍然有限.
研究的目的:
- 系统地审查物理治疗在治疗COVID-19感染后成年人持续性呼吸障碍的有效性.
主要方法:
- 在多个数据库中进行了系统的文献搜索,直到2023年7月.
- 包括接受物理治疗的COVID-19后呼吸障碍的成年人的比较试验.
- 研究的质量使用PEDro尺度进行了评估,并遵循PRISMA指南.
主要成果:
- 19项涉及1292名成年人的研究符合纳入标准,包括15项随机对照试验和4项非随机对照试验.
- 发现有利于物理治疗的显著差异 (SMD -0.63,p < 0.001),具有很高的异质性.
- 小组分析显示,特别是在高强度康复组中显著的积极效应,没有显著的异质性.
结论:
- 物理治疗,特别是肺部康复,可以有效地缓解SARS-CoV-2后呼吸不良患者的呼吸道症状.
- 需要对标准化和详细描述的康复方法进行进一步的研究,以澄清治疗效果并减少可变性.
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