饮食质量模式和慢性病发病率:英国生物银行队列研究
Javier Maroto-Rodriguez1, Rosario Ortolá2, Veronica Cabanas-Sanchez3
1Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Calle del Arzobispo Morcillo, Madrid, Spain.
The American journal of clinical nutrition
|December 12, 2024
概括
坚持特定的饮食,如替代地中海指数 (aMED),停止高血压的饮食方法 (DASH) 和健康的植物性饮食指数 (hPDI),可以降低英国成年人的慢性病 (CKD) 风险. 相反,不健康的植物性和饮食性炎症指数会增加CKD风险.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 关于欧洲人口的饮食和慢性病 (CKD) 风险的研究有限,重点是地中海饮食.
- 这项研究是首次检查多种饮食质量指数和英国成年人中CKD发病率.
研究的目的:
- 调查六种不同的饮食质量指数与英国成年人中CKD发病率之间的联系.
- 评估各种饮食模式对英国一大群人病风险的影响.
主要方法:
- 利用了来自英国生物银行 (2009-2021) 的106,870名参与者的前性队列.
- 用多个24小时的饮食回忆来评估饮食摄入量.
- 应用了六个已建立的饮食质量指数:替代地中海指数 (aMED),2010年替代健康饮食指数,DASH,hPDI,UPDI和DII.
- 通过使用考克斯回归分析的临床记录,注册表和自我报告来确定事件性CKD病例.
主要成果:
- 在9.27年的中位数随访期间,发现了2934例CKD病例.
- 对aMED,DASH和hPDI的更高的坚持与慢性脏病的风险降低有关 (HRs从0.77到0.84).
- 增加对UPDI和DII的坚持与更高的CKD风险有关 (HRs从1.20到1.27).
结论:
- 对aMED,DASH和hPDI饮食模式的更高坚持与英国成年人患CKD风险较低有关.
- 更多地遵守UPDI和DII饮食模式与患CKD的风险增加有关.
- 饮食质量在英国人口中CKD风险分层中发挥着重要作用.
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