在主导左叶的手术后命名物体:风险因素,时间进程和长期结果
Katrin Walther1, Caroline Reindl2, Michael Schwarz2
1Department of Neurology, Universitätsklinikum Erlangen, Erlangen, Bayern, Germany katrin.walther@uk-erlangen.de.
Journal of neurology, neurosurgery, and psychiatry
|December 12, 2024
概括
在主导叶的手术可以损害物体命名. 虽然一些患者康复了,但永久的赤字仍然在26%,根据早期衰退的严重程度可以预测.
科学领域:
- 神经科学是一个神经科学.
- 神经外科 神经外科
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 叶手术可能导致命名缺陷.
- 有限的数据存在于这些程序后的长期命名恢复.
研究的目的:
- 评估叶手术后的短期和长期对象命名结果.
- 确定影响命名恶化和恢复的因素.
主要方法:
- 对象命名 (波士顿命名测试) 评估了手术前,手术后早期 (6-12个月) 和手术后晚期 (≥2年).
- 研究了左侧 (主导) 和右侧 (非主导) 叶切除的患者.
主要成果:
- 在左叶患者中,42%的患者在术后早期经历了命名衰退,而在右叶患者中,这一比例为3%.
- 预测LTLE下降的因素包括较低的手术前口头记忆,较早的发作年龄,后部切除和较晚的发作发作.
- 39%早期衰退的LTLE患者在后期随访时恢复了命名能力,恢复与最初衰退的程度有关.
结论:
- 不到50%的患有主导叶切除的患者表现出显著的命名下降.
- 命名赤字经常显示部分复苏,但26%的赤字是永久的.
- 术后早期命名下降的严重程度预测了长期视觉对象命名结果.
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