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Updated: Jun 5, 2025

Generation of Genome-wide Chromatin Conformation Capture Libraries from Tightly Staged Early Drosophila Embryos
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Published on: October 3, 2018

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调节区域之间的染色体间接触触发了Drosophila中稳定的跨代表观遗传

Maximilian H Fitz-James1, Gonzalo Sabarís2, Peter Sarkies3

  • 1Institute of Human Genetics, CNRS and University of Montpellier, 141 Rue de la Cardonille, 34094 Montpellier, France; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.

Molecular cell
|December 12, 2024
PubMed
概括

德洛索菲拉的跨代表观遗传 (TEI) 涉及Fab-7元素和基因素标记. 像 pleiohomeotic 和 GAGA 因子这样的蛋白质对于通过染色体接触建立和维持 TEI至关重要.

关键词:
3D基因组组织 3D基因组组织在Fab-7中,Fab-7是什么?这就是GAGA因子.染色质接触者 染色质接触者这种表达式叫做"epimutation"或"epimutation".这是一个多重复合材料.跨世代的表观遗传遗传.

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