接受结核病预防治疗的障碍:中国的一项多中心横截面研究
Jingjuan Ren1, Fei Huang1, Haifeng Chen2
1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, Chinese Center for Disease Control and Prevention, Beijing 102206, China;National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
在中国,只有17%的潜伏性结核病感染 (LTBI) 患者接受了结核病预防治疗 (TPT). 关键的障碍包括对有效性的误解和对副作用的担忧.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 卫生政策 卫生政策
背景情况:
- 结核病 (TB) 仍然是一个重大的全球卫生挑战,潜伏结核病感染 (LTBI) 代表了活跃疾病的主要储存库.
- 了解影响结核病预防治疗 (TPT) 普及的因素对于有效的结核病控制策略至关重要,特别是在像中国这样的高负担国家.
研究的目的:
- 调查中国LTBI患者接受TPT的意愿和障碍.
- 为制定有针对性的干预措施提供信息,以改善TPT的普及.
主要方法:
- 从5月到2023年12月,在中国10个县进行了一项多中心的横截面研究.
- 参与者包括医疗保健工作者,学生,教师和其他年龄在15-65岁的人,遵循国家指南.
主要成果:
- 参与者对TPT的整体接受率为17.0% (183/1,077).
- 在不同性别,年龄组,教育水平和职业中观察到TPT接受率的显著差异 (P <0.05).
- 主要障碍包括对TPT预防有效性的误解 (57.8%) 和对潜在副作用的担忧 (32.7%).
结论:
- 对LTBI和TPT的更深入的理解对于在中国扩大TPT计划至关重要.
- 制定针对特定障碍的有针对性的政策是必要的,以增加TPT在不同的人口群体的接受度.
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