探索TGF-β通路活性和对转移性黑色素瘤患者检查点抑制的反应之间的关系

Stefan G van Ravensteijn1, Avital L Amir2, Daniele V F Tauriello3,4

  • 1Department of Medical Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.

PubMed
概括

免疫检查点抑制 (ICI) 是一种黑色素瘤治疗方法,但会发生耐药性. TGF-β途径没有预测耐药性,但刺途径确实如此,表明其作为ICI反应和晚期黑色素瘤生存的生物标志物的潜力.

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