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Updated: Jun 5, 2025

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在前列腺癌细胞中由超生理性雄激素控制的LYL1的功能电路,以调节细胞衰老

Mehdi Heidari Horestani1, Katrin Schindler1, Aria Baniahmad2

  • 1Institute of Human Genetics, Jena University Hospital, Am Klinikum 1, 07740, Jena, Germany.

Cell communication and signaling : CCS
|December 12, 2024
PubMed
概括

超生理的雄激素水平 (SAL) 诱导前列腺癌 (PCa) 中的细胞衰老,通过通过BHLHE40.0.上调LYL1. 这一途径涉及新的反循环和AR-BHLHE40/LYL1-p27kip1轴,为PCa提供了新的治疗点.

关键词:
雄激素受体的受体 雄激素受体由雄激素诱导的细胞衰老.LYL1 LYL1 这是一个很好的例子.前列腺癌是什么意思 前列腺癌是什么意思

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