相关实验视频
Updated: Jun 5, 2025

03:36
Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
381
2022年全球食道癌流行病学和2050年的预测:基于GLOBOCAN数据的全面分析和预测
Ling Qi1, Mengfei Sun2, Weixin Liu3
1Department of Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100021, China.
Chinese medical journal
|December 13, 2024
概括
食道癌仍然是一个重要的全球健康问题,预计到2050年,食道癌的病例将增加80%. 改变生活方式和公共卫生政策对于减少这种癌症负担至关重要.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 食道癌对全球健康造成重大负担,区域差异很大.
- 了解当前趋势和未来预测对于有效的公共卫生战略至关重要.
研究的目的:
- 分析2022年全球185个国家的食道癌症负担.
- 预测到2050年食道癌发病率和死亡率的未来趋势.
主要方法:
- 利用GLOBOCAN 2022数据库从185个国家的食道癌数据.
- 根据人类发展指数 (HDI) 和地区分层计算的年龄标准化发病率和死亡率 (ASIR/ASMR).
- 预计2050年趋势假设2022年发生率和死亡率风险保持不变,考虑到人口变化.
主要成果:
- 在2022年,全球记录了511,054例新的食道癌症病例和445,391例死亡.
- 在东非,东亚,南非和中南亚观察到的最高率.
- 食道癌在18/25个国家/地区分别是癌症发病率/死亡率的前五大原因. 中国占全球病例/死亡人数的43%.
- 高人类发展指数的国家承受着最大的负担;男性的发病率/死亡率明显高于男性.
- 预计到2050年,病例和死亡人数将分别增加约80.5%和85.4%.
结论:
- 食道癌继续成为全球严重的疾病.
- 促进健康的生活方式 (减少烟草/酒精,改善饮食) 可以减轻风险.
- 基于证据的公共卫生政策对于减少全球疾病负担至关重要.
相关概念视频
Barrett Esophagus-I: Introduction
64
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
64
Cancer Survival Analysis
328
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
328
Barrett Esophagus-II: Clinical Manifestations and Management
104
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
104
Esophagus
615
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
615
Esophageal Strictures-II: Clinical Features and Management
47
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
47
Esophageal Varices-II: Clinical Features and Management
46
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
46

