运动与人造重力相结合,以及仅以运动为对策,可以防止由55天的HTT床位休息引发的器官和血管形态变化
P Arbeille1, K Zuj1, L Guillon1
1UMPS-CERCOM (Unit Med Physiol Spatiale) Faculte de Medicine Universite de Tours, Tours, France.
Frontiers in physiology
|December 13, 2024
概括
俯卧床 (HDT) 改变了心血管和器官的测量. 运动和人工重力运动对策部分缓解了这些变化,人工重力对动脉延展能力有更大的影响.
科学领域:
- 生理学 生理学 生理学
- 太空医学 太空医学
- 医疗成像医学成像
背景情况:
- 太空飞行和卧床等极端环境会引起生理变化.
- 之前的研究指出了血管变化;这项研究调查了更广泛的器官系统影响.
- 超声波成像,适用于太空任务,用于评估这些变化.
研究的目的:
- 用超声波评估55天俯卧床 (HDT) 对心血管和器官参数的影响.
- 评估有氧运动 (EX) 和人工重力运动 (EX-AG) 的有效性,作为对抗HTT诱导的变化的对策.
- 为了比较EX与EX-AG在减轻超声波测量变化的疗效.
主要方法:
- 24名参与者接受了55天的HDT,分为控制 (被动HDT),EX和EX-AG组.
- 在HDT前和55日,对10个器官/血管的15个参数进行了超声波测量.
- 器官/血管包括动脉,大动脉,左心室,脏和巨大的中间肌肉.
主要成果:
- 高强度测试导致多个测量参数发生显著变化.
- Carotid intima-media 厚度 (IMT) 和延展性,心脏喷射率,门静脉直径和肌肉厚度都受到影响.
- 无论EX还是EX-AG都减轻了一些HDT诱导的变化,EX-AG对状动脉张张能力表现出更好的影响.
结论:
- 55天的HDT会导致各种器官和心血管结构的可测量变化.
- 有氧运动和人工重力运动提供了对这些HTT效应的部分保护.
- 人工重力运动在模拟微重力时,在维护血管功能方面具有潜在的更大的益处.
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