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使用电治疗治疗双相情感障碍的经验:北印度的一项回顾性研究

Sandeep Grover¹, Namita Sharma¹, Subho Chakrabarti¹

¹Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Indian journal of psychiatry

|December 13, 2024

概括

电疗法 (ECT) 是有效的双相情感障碍 (BD) 在印度,超过75%的响应在三分之二的患者. 这种治疗在抑郁和躁狂发作中表现出显著的疗效.

科学领域:

精神病学是一个精神病学.
神经科学是一个神经科学.
临床医学临床医学

背景情况:

有限的数据存在电疗法 (ECT) 在印度患有双相情感障碍 (BD) 的患者的有效性.
了解不同人群的治疗反应对于优化护理至关重要.

研究的目的:

评估接受ECT的印度BD患者的社会人口和临床资料.
为了比较双极性抑郁症治疗结果与躁狂/混合发作.
为了确定在BD中ECT反应的预测因子.

主要方法:

从ECT注册表中对278名BD患者的325个ECT疗程进行了回顾性分析.
根据情节类型对ECT疗程的分类:双极性抑郁症 (n=202) 和躁狂/混合情节 (n=123).
基于百分比改善的治疗反应的评估.

主要成果:

观察到高响应率: 63.3%的患者有>75%的改善,大约90%的患者有>50%的改善.
电脑心电疗法在双极性抑郁症和躁狂/混合发作中表现出显著的疗效.
抑郁和躁狂/混合发作之间的ECT反应率没有显著差异.

结论:

在印度人群中,ECT是治疗双相情感障碍 (BD) 的高效疗法.
大约三分之二的BD患者经历了ECT>75%的症状改善.
在BD的抑郁和躁狂/混合阶段,ECT为患者提供了实质性的益处.

关键词:

双极性障碍是一种双极性障碍.一个抑郁的情节.电疗法是一种电疗法.躁狂发作是一个躁狂发作.治疗反应治疗反应.

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Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...