面包消费和癌症风险:前性队列研究的系统审查和元分析
Glenn A Gaesser1, Siddhartha S Angadi2, Craig Paterson3
1College of Health Solutions, Arizona State University, Phoenix, AZ, United States.
Current developments in nutrition
|December 13, 2024
概括
面包消费不会增加癌症的风险. 根据系统性审查和元分析,高摄入全谷物面包与降低癌症死亡率和降低结直肠癌风险有关.
科学领域:
- 营养流行病学 营养流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 面包消费在全球范围内很普遍.
- 烯胺是一种潜在的致癌物质,可以存在于面包中.
- 关于面包摄入量与癌症风险之间的关联存在担忧.
研究的目的:
- 系统地审查和对现有研究进行元分析.
- 为了确定面包消费是否与癌症风险增加有关.
- 研究全谷物面包对癌症风险的影响.
主要方法:
- 对前性队列研究进行系统审查和元分析.
- 搜索了PubMed和Medline数据库,截至2024年3月1日.
- 包括24个出版物,其中包含来自1,887,074名成年人的数据.
主要成果:
- 总体面包摄入量与特定部位的癌症风险没有关联 (HR:1.01;95% CI:0.89,1.14).
- 面包消费与总癌症死亡率没有联系 (HR:0.90;95% CI:0.73,1.11).
- 较高的全谷物/非白面包消费与较低的癌症风险有关,特别是结肠直肠癌.
结论:
- 面包消费与特定癌症的风险增加无关.
- 摄入全谷物或非白面包与减少癌症死亡率和结直肠癌风险相关.
- 研究结果表明,全谷物面包对某些癌症有保护作用.
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