电子健康,环境和DNA (EXCEED) 扩展队列COVID-19关注点
Paul H Lee1, Anna L Guyatt1, Catherine John1
1Department of Health Sciences, University of Leicester, Leicester, UK.
Wellcome open research
|December 13, 2024
概括
电子健康,环境和DNA (EXCEED) 研究的扩展队列收集了COVID-19数据,没有发现慢性疾病和感染之间有明确的联系. 大多数参与者在没有先前感染的情况下显示了疫苗接种证据.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 基因组学就是基因组学.
背景情况:
- 纵向人口研究提供了对COVID-19风险因素和流行病影响的见解.
- 电子健康,环境和DNA (EXCEED) 的扩展队列是一个大型,成熟的队列,具有广泛的数据链接.
- EXCEED现有的数据包括电子健康记录,螺旋计,基因组学和问卷.
研究的目的:
- 调查大量人口队列中的COVID-19的风险因素和后果.
- 评估COVID-19大流行对一般福祉的间接影响.
- 用新的COVID-19特定数据来丰富EXCEED队列.
主要方法:
- 对EXCEED参与者 (2020年5月至2021年7月) 进行了新的COVID-19问卷调查.
- 在线系统促进了新参与者招募和数据收集.
- 在COVID-19血清学子研究中,使用了家庭抗体检测套件.
主要成果:
- 3,693名参与者提供了COVID-19感染状况;趋势反映了国家数据.
- 对2,768名参与者的回归分析显示,慢性疾病计数和COVID-19感染之间没有明确的关系.
- 在有血清检查结果的2,144名参与者中,8.5%有先前感染,85.9%显示没有感染的疫苗接种.
结论:
- 用COVID-19数据丰富EXCEED队列可以提高对大流行影响的理解.
- 这项研究提供了有关感染,疫苗接种和慢性疾病关联的宝贵数据.
- 研究人员可以通过申请EXCEED研究获得数据.
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