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基于结构的向脂质A修饰酶PmrC以对抗Acinetobacter baumannii中的胆固醇抗性

Maria Romano1, Federico Falchi2,3, Eliana De Gregorio4

  • 1Department of Biomedical Sciences, Institute of Biostructures and Bioimaging, National Research Council (CNR), Napoli, Italy.

Frontiers in microbiology
|December 13, 2024
PubMed
概括

研究人员发现了一种新型化合物,s-Phen,可以抑制PmrC蛋白,这是Acinetobacter baumannii.在胆固醇抵抗中的关键因素. 这一发现提供了一种新的策略,通过使最后的抗生素再次有效地对抗多药耐药性病原体.

关键词:
细胞壁上的细胞壁.科里斯抗性的抗性的 pEtN 转移酶.蛋白质结构 蛋白质结构虚拟选 虚拟选 虚拟选

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