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Updated: May 10, 2026

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
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Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans

Published on: August 16, 2017

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一个途径级信息提取R (PLIER) 框架,以获得对唐氏综合征肥胖症的机制性见解

Sutanu Nandi1, Yuehua Zhu2, Lucas A Gillenwater1

  • 1Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
|December 13, 2024
PubMed
概括

唐氏综合症 (DS),以21号染色体的三倍化为特征,通常涉及肥胖. 一个新的全PLIER模型揭示了链接DS和肥胖的分子途径,识别了GPX1.1等关键基因.

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A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information05:01

A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies14:56

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

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相关概念视频

Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...