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Updated: Jun 5, 2025

Spheroid Assay to Measure TGF-β-induced Invasion
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HIF1α/TIMP1/MT6-MMP通路的激活与垂体虚细胞腺瘤的入侵有关

Shengyuan Yu, Quanxi Duan, Changcun Niu

    Endocrine-related cancer
    |December 13, 2024
    PubMed
    概括

    缺氧诱导因子1-α (HIF1α) 通过调节TIMP1和MT6-MMP,而不是通过表皮-介质细胞过渡 (EMT) 来促进 pituitary null cell adenoma 侵袭. 这一途径是理解侵袭性非功能性垂体腺瘤的关键.

    关键词:
    这就是HIF1α.在MT6-MMP中使用.这是入侵的入侵.不起作用的垂体腺瘤.没有细胞腺瘤.

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