好是多么好的 足够好吗? 什么应该是CRC查的目标?
David Lieberman1, Evelien Dekker2
1Professor Emeritus, Division of Gastroenterology and Hepatology, Department of Medicine, Oregon Health and Science University, L461, 3181 SW Sam Jackson Park Road, Portland, OR, 97239, USA. lieberma@ohsu.edu.
Digestive diseases and sciences
|December 13, 2024
概括
结肠直肠癌 (CRC) 查有效降低死亡率和发病率. 侵入性结肠镜检查和非侵入性便检查都有助于预防和早期检测,坚持和质量是关键因素.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 结肠直肠癌 (CRC) 查已被证明可以降低平均风险人群的死亡率和发病率.
- 查通过去除前体病变 (CPL) 来预防癌症,并通过检测可治愈的CRC来降低死亡率.
- 可治愈的CRC和CPL都是查干预的目标.
研究的目的:
- 为了比较不同结直肠癌查方式的有效性.
- 评估非侵入性便检查和侵入性结肠镜检查在预防和检测CRC中的作用.
- 确定结直肠癌查计划有效性的关键决定因素.
主要方法:
- 审查目前关于非侵入性便测试和用于CRC查的侵入性结肠镜检查的证据.
- 查目标的分析,包括可治愈的CRC和癌症前体病变 (CPL).
- 考虑程序的坚持和质量作为影响有效性的因素.
主要成果:
- 非侵入性便测试是多步骤的,检测可治疗的癌症,但相比侵入性查,检测CPL的可能性较低.
- 侵入性结肠镜检查是一种高质量性能的一步检测,有效检测可治愈的CRC和CPL.
- 这两种查方法都可以有效,尽管它们的主要目标有所不同.
结论:
- 患者的坚持和计划质量是任何结直肠癌查计划成功的关键决定因素.
- 非侵入性和侵入性查之间的选择可能取决于计划实施因素和患者的坚持.
- 有效的CRC查策略依赖于适当的测试和持续的患者参与的结合.
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