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Updated: Jun 18, 2026

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在NMDA受体脑炎中,患者报告的结果措施

Josephine Heine1, Ole Jonas Boeken1, Sophia Rekers1,2

  • 1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Neurology and Experimental Neurology.

Neurology(R) neuroimmunology & neuroinflammation
|December 13, 2024
PubMed
概括

持续的神经精神症状和认知问题显著影响N-甲基-D-酸盐受体 (NMDAR) 脑炎幸存者的生活质量. 应对策略,而不是疾病严重程度,预测长期与健康相关的生活质量 (HRQoL).

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Encephalitis l: Introduction01:19

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...