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Updated: Jun 5, 2025

Corneal Confocal Microscopy: A Novel Non-invasive Technique to Quantify Small Fibre Pathology in Peripheral Neuropathies
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角膜共聚焦显微镜识别和区分患有多发性硬化和的患者

Ioannis N Petropoulos1, Kareem Essam Aly1, Shaikha Al-Thani1,2

  • 1Division of Research, Weill Cornell Medicine Qatar, Doha, Qatar.

Translational vision science & technology
|December 13, 2024
PubMed
概括

使用共聚焦显微镜进行角质神经分析,可以区分多发性硬化症 (MS) 和患者. 角膜中的这些神经退行性模式为这些疾病提供了潜在的诊断生物标志物.

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Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
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