DCP1A是一种MEK基质,调节小鼠胚胎干细胞的自我更新和分化

Jiayu Yu1, Nannan Zhao1, Yuying Wang1

  • 1State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Protein Sciences, Frontiers Science Center for Cell Responses, National Demonstration Center for Experimental Biology Education and College of Life Sciences, Nankai University, Tianjin 300071, China.

Cell reports
|December 13, 2024
PubMed
概括

基因激活的细胞外信号调节激酶 (MEK) 在转录后调节基因表达. DCP1A的MEK酸化控制RNA处理,影响胚胎干细胞的自我更新和通过加工机体的分化.