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Updated: Jun 5, 2025

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在复制应激过程中,PNKP保护了受阻的复制分叉免受核酶依赖的降解

Fatemeh Mashayekhi1, Cassandra Ganje1, Marie-Christine Caron2

  • 1Department of Oncology, Faculty of Medicine & Dentistry, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.

Cell reports
|December 13, 2024
PubMed
概括

聚核酸酶-酸酶 (PNKP) 防止在停滞的复制叉 (RF) 中过度的DNA降解. PNKP的损失导致新生的DNA降解,突出了PNKP.

关键词:
这就是为什么CPCPCPCPCP修复DNA的修复DNA的修复时间 EXO1 EXO1叉子反转 叉子反转在MRE11中,MRE11是MRE11中的一个.分子生物学分子生物学在PNKP中,PNKP是最重要的.拓糖酶 1 的作用.基尿素的含量是多少复制压力是复制的压力.里核酸的错误整合

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