心房和心室功能性腹:患病率,特征,结果和疾病进展
Qin-Fen Chen1,2, Xi Zhou3, Christos S Katsouras4
1Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Ouhai District, Wenzhou 325000, China.
European heart journal. Cardiovascular Imaging
|December 13, 2024
概括
这项研究揭示了对心房 (AFMR),心室 (VFMR) 和双功能 mitrale regurgitation (FMR) 的明显结果. 双重FMR呈现出不良预后,而VFMR与AFMR相比显示出更高的死亡率和进展风险.
科学领域:
- 心脏病学 心脏病学
- 心脏成像 - - 心脏成像
- 心脏衰竭研究研究
背景情况:
- 有限的数据存在于功能性心肌反 (FMR) 亚型的自然史:心房 (AFMR),心室 (VFMR) 和双重FMR.
- 了解这些亚型的患病率,特征和结果对于患者管理至关重要.
研究的目的:
- 检查AFMR,VFMR和双重FMR的患病率,特征,临床结果和心声学进展.
- 为了比较与每个FMR亚型相关的风险,关于死亡率,心力衰竭住院和疾病进展.
主要方法:
- 连续出现至少轻度至中度FMR的患者的回顾性分析.
- 分类为AFMR (左心房扩大),VFMR (左心室扩大或减少喷射分数) 或双重FMR.
- 评估临床结果 (所有原因的死亡率,高频率住院) 和心声学结果 (进展到严重的FMR或双重FMR).
主要成果:
- 双性FMR是最常见的亚型 (47%),其次是AFMR (39%) 和VFMR (14%).
- 双重FMR显示出所有原因死亡率和心力衰竭住院治疗的最高风险.
- 与AFMR相比,VFMR与死亡率 (aHR=1.73) 和HF住院 (aHR=1.23) 的风险明显增加. 与AFMR相比,VFMR也显示了严重FMR (1.51倍) 和双重FMR (3.08倍) 的进展.
结论:
- 前庭和心室FMR在生存和疾病进展方面表现出显著的差异.
- 双重FMR代表了一种独特而常见的疾病过程,通常是从AFMR或VFMR发展起来的,并且与预后不佳有关.
- 室腔FMR对不良临床结果和疾病进展的风险比心房FMR更大.
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