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Updated: Jun 5, 2025

Analyses of Actin Dynamics, Clutch Coupling and Traction Force for Growth Cone Advance
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Published on: October 21, 2021

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整合素粘合体轴抑制RPM-1无处不在酶信号中心,以调节生长和轴突发育

Jonathan Amezquita1,2, Muriel Desbois3, Karla J Opperman1

  • 1Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington, United States of America.

PLoS genetics
|December 13, 2024
PubMed
概括

整合素粘合体通路,包括Talin (TLN-1),Kindlin (UNC-112),和β-整合素 (PAT-3),通过抑制RPM-1 (MYCBP2),对神经发育和预防大脑疾病至关重要,调节轴突终结.

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