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Updated: Jun 5, 2025

Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level
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Published on: July 26, 2024

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所有真核细胞SMC蛋白质在每个DNA循环挤出步骤中都会诱导0.6的扭曲

Richard Janissen1,2, Roman Barth1, Iain F Davidson3

  • 1Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, 2629HZ, Netherlands.

Science advances
|December 13, 2024
PubMed
概括

染色体结构维护 (SMC) 复合体通过循环挤出重塑DNA. 这三种真核细胞SMC复合体都在DNA循环挤出过程中诱导显著的负转,揭示了一个保存的机制.

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