基因组印记和环境表观遗传学:它们对绵羊的繁殖特征的影响跨平价
Fatemeh Tavasolian1, Mohsen Gholizadeh1, Hasan Hafezian1
1Department of Animal Science, Faculty of Animal Science and Fisheries, Sari Agricultural Sciences and Natural Resources University, Sari, Iran.
Animal reproduction science
|December 13, 2024
概括
基因组印记显著影响了Baluchi羊的生殖特征. 在育种计划中包括这些印记效应可以提高遗传评估准确性,例如子重量等特征.
科学领域:
- 动物遗传学和动物繁殖
- 生殖生物学 生殖生物学
- 基因组印记是一种基因组印记.
背景情况:
- 基因组印记是一种基因以父系原始特异的方式表达的现象,可以影响定量特征.
- 了解印记效应对于准确的牲畜遗传评估至关重要,特别是对于经济上重要的生殖特征.
- 之前的研究已经表明了印记在绵羊繁殖中的潜在作用,但需要进行跨平价性综合分析.
研究的目的:
- 调查基因组印记对Baluchi绵羊关键生殖特征的遗传变异的影响.
- 估计直接和母性遗传性,以及母性和父性印记遗传性,用于三个平价的子体重特征.
- 确定是否有必要将印记效应纳入Baluchi绵羊繁殖计划的遗传评估模型.
主要方法:
- 应用了一种单变线性动物模型来分析每只出生羔羊的 litter 平均重量 (LMWLB),每只断奶羔羊的 litter 平均重量 (LMWLW),出生时的 litter 总重量 (TLWB) 和断奶时的 litter 总重量 (TLWW).
- 在模型中,三种平价的表现被视为单独的特征.
- 评估了24种动物模型,包括直接的附加遗传效应,母性遗传效应,母性永久环境效应,遗传共变性和母/父印记效应. 模型选择使用了Akaike的信息标准 (AIC).
主要成果:
- 研究的特征的直接遗传概率估计一般较低,值在LMWLW的0.039 ± 0.017到TLWW的0.085 ± 0.028之间.
- 对于TLWB,LMWLB,TLWW和LMWLW的母性印记遗传概率估计在均值中显著,其值从0.048 ± 0.016到0.085 ± 0.021.
- 父亲印记遗传概率估计始终低于母亲印记估计,大多数值在所有特征和均值中接近零.
结论:
- 基因组印记,特别是母体印记,在Baluchi羊的生殖特征的遗传变异中起着重要作用.
- 研究结果表明,印记效应应纳入遗传评估模型,以提高育种计划的准确性.
- 准确的基因评估包括印记可以导致更有效的选择策略,以提高Baluchi绵羊的繁殖性能.
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