促进喘的预防和向喘缓解:EUFOREA关于提高喘护理标准的共识声明
Milos Jesenak1, Anna Bobcakova1, Ratko Djukanovic2
1Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Department of Pulmonology and Phthisiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Institute of Clinical Immunology and Medical Genetics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia.
个性化喘管理对于无法控制的严重喘至关重要. 转向以表型和内型为目标的方法可以改善结果和生活质量.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 过敏和免疫学 过敏和免疫学
- 临床药理学 临床药理学
背景情况:
- 喘显著影响生活质量,尽管在理解表型和内型方面取得了进展.
- 很大一部分患者患有无法控制的严重喘,有恶化的风险,需要全身皮质类固醇.
- 目前的指导方针建议对不受控制的严重喘进行个性化管理.
研究的目的:
- 总结目前的概念和专家建议,以优化喘护理.
- 倡导早期实施个性化喘管理策略.
- 为了防止系统性皮质类固醇的过度使用,并减轻严重喘患者的疾病进展.
主要方法:
- 召集欧洲过敏和呼吸道疾病研究和教育论坛 (EUFOREA) 专家小组.
- 讨论和达成共识,以解决失控严重喘的策略.
- 审查当前对喘表型和内型的理解.
主要成果:
- 一种共识观点,倡导一种整体的,个性化的喘管理方法.
- 在疾病管理中早期实施表型和内型向策略的理由.
- 确定未来临床试验和人口研究的未满足需求.
结论:
- 从症状驱动转向个性化,有针对性的喘管理至关重要.
- 早期,个性化的治疗可以制疾病的进程,并改善临床结果.
- 建议采用整体方法,以保持喘患者与健康有关的生活质量.
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