相关实验视频

Updated: Jun 5, 2025

Chemical Amputation and Regeneration of the Pharynx in the Planarian Schmidtea mediterranea
06:14

Chemical Amputation and Regeneration of the Pharynx in the Planarian Schmidtea mediterranea

Published on: March 26, 2018

10.8K

在平面再生过程中,FoxO对于新芽细胞分化是必需的

Hanxue Zheng1, Linfeng Li1, Du Wang1

  • 1Laboratory of Tissue Engineering, College of Life Sciences, Northwest University, Xi'an, China.

International journal of biological macromolecules
|December 13, 2024
PubMed
概括

叉头盒O (FoxO) 信号传递对于平面再生至关重要,它调节干细胞分化而不是增殖. 抑制FoxO通过影响原生细胞的产生,损害组织再生,为再生疗法提供了洞察力.

关键词:
不同化的差异化埃尔克路径的路径福克斯OOO 在线观看平面再生的平面再生.干细胞是一种干细胞.

更多相关视频

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development14:08

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development

Published on: January 26, 2013

15.2K
Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica09:58

Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

Published on: August 31, 2011

37.0K

相关概念视频

Whole Body Regeneration01:33

Whole Body Regeneration

Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
3.3K
Role Of Notch Signalling In Intestinal Stem Cell Renewal01:12

Role Of Notch Signalling In Intestinal Stem Cell Renewal

Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
2.1K
Methods of Nuclear Reprogramming01:24

Methods of Nuclear Reprogramming

Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for...
1.8K
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
717
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.2K