在NIH工具箱情绪电池测量和以前的双相I型精神障碍的自杀企图之间的关联
Noah M Gritters1, Gail I S Harmata2, Deniz Buyukgok3
1Carver College of Medicine, The University of Iowa, IA, United States; Department of Radiology, The University of Iowa, IA, United States.
Journal of affective disorders
|December 13, 2024
概括
两极性I型障碍 (BD-I) 患者之前曾尝试过自杀,表现出不同的情绪模式. 美国国立卫生院工具箱情绪电池 (NIHTB-EB) 有效地识别了这些模式,超过了传统的情绪尺度.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 神经科学是一个神经科学.
背景情况:
- 与普通人群相比,双相I型精神障碍 (BD-I) 患者的自杀尝试明显更为常见.
- 之前关于BD-I中自杀的研究主要使用了孤立的情感测试或临床医生评级的尺度,在探索简短的,多维的自我报告措施方面留下了一个空白.
研究的目的:
- 在BD-I患者中使用NIH工具箱情绪电池 (NIHTB-EB) 评估情绪指标.
- 确定哪些NIHTB-EB措施与BD-I.自杀企图的历史有关.
- 评估NIHTB-EB在通过机器学习识别过去的自杀企图方面的有效性,并将其性能与临床情绪尺度进行比较.
主要方法:
- 该研究包括39名BD-I患者和有过自杀未遂的参与者,48名BD-I患者没有过自杀未遂的参与者,以及58名对照组.
- 参与者完成了NIH工具箱情绪电池 (NIHTB-EB) 和临床情绪量表.
- 机器学习模型,包括随机森林,用于分析数据并比较预测准确性.
主要成果:
- 在17项NIHTB-EB测量中,有9项与BD-I患者先前的自杀企图有显著的关联.
- 随机森林模型确定的关键区分变量包括感知到的压力,情感支持,愤怒敌意,愤怒身体攻击,感知到的拒绝,孤独和自我效能.
- 使用NIHTB-EB测量的模型在识别过去的自杀企图方面取得了更高的准确性 (69.0%70.1%),而仅使用临床情绪尺度的模型 (57.5%).
结论:
- 该NIHTB-EB作为一个实用和可部署的工具,以了解情感相关因素在BD-I患者自杀中的作用.
- 由NIHTB-EB确定的特定情感领域显示出未来纵向研究和旨在预防自杀的干预措施的目标的希望,在BD-I.
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