针对近视的重复低水平红光治疗的安全性:系统性审查
Yanping Chen1, Ruilin Xiong1, Shaopeng Yang1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou 510060, China.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
|December 13, 2024
概括
针对近视的重复低水平红光 (RLRL) 治疗显示出良好的安全性,没有报告可逆性视力丧失. 建议监测视觉敏度和后视图,以管理暂时的副作用.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 公共卫生 公共卫生
背景情况:
- 近视的患病率在全球范围内不断增加,需要有效和安全的干预措施.
- 重复的低水平红光 (RLRL) 治疗正在成为近视的潜在治疗方法.
- 确定RLRL治疗的安全性对于其临床采用至关重要.
研究的目的:
- 系统地审查和确定RLRL治疗近视的安全性概况.
- 评估与RLRL治疗相关的副作用的发生率和性质.
- 为了比较RLRL治疗与其他近视控制方法的风险对益率.
主要方法:
- 使用近视和RLRL治疗的关键词对七个数据库的系统审查 (开始-2024年2月).
- 对安全结果,风险与益处比率以及副作用发生率的综合分析.
- 将RLRL副作用与已建立的反迷恋干预措施进行比较.
主要成果:
- 分析了20项研究 (2380名参与者,1436人接受RLRL);中位数随访时间为9个月.
- 没有报告永久视力丧失或眼睛结构损伤的病例.
- 暂时的后图像 (在6分钟内解决) 是最常见的副作用;发生率为每100个患者年0.088.
结论:
- 在近视治疗中,RLRL治疗似乎是安全的,没有发现不可逆转的视力或结构损伤.
- 建议监测视力敏度和影像后持续时间,以检测短暂的副作用.
- 需要进一步的长期,充足的研究来充分确定RLRL治疗的安全性.
相关概念视频
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...