不同的自粘树脂水泥和通过的固化对牙纤维细胞的影响
Kittipat Termteerapornpimol1, Karn Tongchairati2, Narin Intarak2
1Center of Excellence in Genomics and Precision Dentistry, Clinical Research Center, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand; Oral Biology Program, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
International dental journal
|December 13, 2024
概括
与RelyX U200 (RX) 相比,Maxcem Elite Chroma (MC) 水泥,特别是当通过体进行光固化时,显著降低了人类牙纤维细胞活力,并延迟了伤口愈合. 仔细选择水泥和固化对于牙周健康至关重要.
科学领域:
- 牙科材料科学 牙科材料科学
- 生物材料是一种生物材料.
- 牙周病学 牙周病学
背景情况:
- 自粘树脂水泥 (SARCs) 是固定假牙的组成部分.
- 沙尔克及其化物对牙周组织的潜在细胞毒性作用需要研究.
- 了解这些影响对于保持牙健康至关重要.
研究的目的:
- 评估人类牙纤维细胞 (HGFs) 对两种SARC的化物在体外反应.
- 在模拟的临床条件下比较RelyX U200 (RX) 和Maxcem Elite Chroma (MC) 的生物效应.
- 评估不同固化方法,包括通过石固化对SARC化物细胞毒性的影响.
主要方法:
- 两种SARC (RX和MC) 用各种固化方法 (光固化,通过1或2毫米硬化,自我固化) 聚合.
- HGFs暴露在不同度的SARC化物中.
- 评估的终点包括细胞活力,活力,伤口愈合能力和基因表达 (NRF2).
主要成果:
- 自固化MC和通过2毫米合金固化的MC显著降低了HGF的活力和活力.
- MC化物表现出比RX化物更大的细胞毒性.
- 伤口愈合受到了MC通过合金治愈的损害,NRF2表达增加表明氧化应激.
- 石对RX治疗细胞的伤口愈合没有显著影响.
结论:
- 马克塞姆精英染色体 (MC),特别是通过石化时,对牙组织健康构成风险.
- 这些发现强调了选择适当的SARC和治愈方案的重要性,以尽量减少牙周不良影响.
- 临床实践应优先考虑支持最佳的牙组织反应和愈合的水泥和固化方法选择.
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