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探索作为潜在的抗糖尿病剂的thiazolidinedione-naphthalene类似物:设计,合成,分子对接和体外评估

Sharfuddin Mohd1, Vikas Sharma1, Vancha Harish1

  • 1School of pharmaceutical sciences, Lovely Professional University, Phagwara, Punjab, India.

Cell biochemistry and biophysics
|December 13, 2024
PubMed
概括

新的 thiazolidinedione-naphthalene 化合物通过抑制胰腺α-氨基酶 (PAA) 和肠道α-葡萄糖酶 (IAG) 显示出有前途的抗糖尿病活性. 化合物17e显示出优异的抑制作用和抗氧化潜力,证实其作为潜在的抗糖尿病药物的可行性.

关键词:
抗氧化剂是一种抗氧化剂.糖尿病 糖尿病 糖尿病肠道中的α-葡萄糖酶.纳夫塔利尼 纳夫塔利尼 纳夫塔利尼 纳夫塔利尼胰腺α-氨酸酶的使用硫酸二氨酸是一种硫酸二.

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