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Updated: Jun 5, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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MYC基因变异的计算分析:非同义SNP的结构和功能影响

Plabita Bhuyan1, Varshabi Bharali1, Sangju Basumatary1

  • 1Department of Biotechnology, Gauhati University, Guwahati, Assam, 781014, India.

Journal of applied genetics
|December 13, 2024
PubMed
概括

这项研究确定了21种有害的MYC基因变异 (nsSNP),这些变异可能会破坏蛋白质相互作用并破坏MYC的稳定,影响癌症的发展. 这些发现有助于理解MYC.

关键词:
在体内进行分析.BHLH-LZ 蛋白质中的一个.在MYC-MAX中使用MYC-MAX二元化.分子相互作用分子相互作用.蛋白质的稳定性 蛋白质的稳定性

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