燃烧口腔综合征的潜在因素:从网络角度的路线图
Oscar Gabriel Castaño-Joaqui1, Laura Jiménez Ortega2,3,4, Rocío Cerero Lapiedra5
1Department of Conservative Dentistry and Bucofacial Prosthesis, Faculty of Odontology, Complutense University of Madrid, Madrid, Spain.
Oral diseases
|December 14, 2024
概括
燃烧口腔综合征 (BMS) 与胃肠道问题和维生素D缺乏有关. 皮质醇起着调解作用,而中央敏感性症状可能预测BMS.
科学领域:
- 口腔医学是指口腔医学.
- 心理神经免疫学 心理神经免疫学
- 营养科学 营养科学
背景情况:
- 燃烧口腔综合征 (BMS) 是一种复杂的口腔面部疼痛状况,病因不明.
- 在BMS的发病过程中,可疑存在包括生物,心理和社会方面的多因素影响.
研究的目的:
- 阐明生物,心理和社会因素之间的复杂关系,有助于燃烧口腔综合征.
- 确定关键变量及其关联途径在BMS的发展和表现.
主要方法:
- 一项涉及82名参与者的病例对照研究 (40例,42例对照).
- 分析80个变量,使用基于规范部分相关性的网络模型进行分析.
- 调查各种因素与BMS之间的直接和间接关联.
主要成果:
- 与BMS的直接关联包括胃肠道变化,维生素D缺乏,肌肉骨变化和症状严重程度评分2 (SSS2).
- 皮质醇变化显示出身体和心理因素之间的直接关联和中介途径.
- SSS2成为BMS预测中最有影响力的因素.
结论:
- 胃肠道变化和维生素D缺乏症显著影响BMS.
- 皮质醇在BMS中调解身体,营养,睡眠和认知因素之间的复杂相互作用.
- 虽然焦虑和抑郁等心理因素是相关的,但中央敏感性症状显示BMS最具预测潜力.
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