相关实验视频
Updated: Jun 5, 2025

08:57
Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
Published on: August 14, 2018
15.8K
[属]_[物种]; 呈现族系来促进合成
Douglas Chesters1,2, Silas Bossert3, Michael C Orr4
1Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Cladistics : the international journal of the Willi Hennig Society
|December 14, 2024
概括
为了改进生命之树的合成,出版的族谱必须包括机器可读的树格式. 在家系学数据中标准化终端格式化可以增强科学合成和下游应用.
科学领域:
- 进化生物学 进化生物学
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
背景情况:
- 发表的族谱对于合成生命之树和支持下游研究至关重要.
- 然而,大量的研究没有以完全可合成的格式呈现家族遗传数据,这阻碍了科学进步.
研究的目的:
- 审查当前的遗传学陈述实践,并确定数据合成的障碍.
- 提出关于出版基因数据的标准化指导方针,以提高其可用性,并促进创建一个全面的生命树.
主要方法:
- 在已发表的研究中对全系遗传呈现格式的审查.
- 分析阻碍进一步计算和手动分析遗传学数据的方面.
- 提议一个正式的语法,用于标准化后代终端格式化.
主要成果:
- 只有不到一半的研究在补充材料中以机器可读的树格式 (例如,Newick) 提供其主要的家族遗传结果.
- 机器可读树的格式存在显著差异,复杂的解析和数据集成.
- 遗传学图像也表现出绘图风格的变化,需要自动转录工具来提取数据.
结论:
- 为机器可读的家族遗传树实施标准化格式对于实现大规模数据合成至关重要.
- 对文件命名,终端标签和数据划分器的明确指导方针将大大提高已发布的族系学的实用性.
- 开发自动化工具来转录来自遗传图像的数据是必要的,以将现有的研究纳入生命之树.
相关概念视频
Evolutionary Relationships through Genome Comparisons
5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
Phylogenetic Trees
45.2K
Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
45.2K
Phylogeny
43.6K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
43.6K
Gene Evolution - Fast or Slow?
7.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.0K
Synteny and Evolution
3.2K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.2K
Microbial Classification System
Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...

