咖啡消费与患有中风高发病率的患者更好的认知表现相关
Massimo Barbagallo1,2, Anne Springer3,4, Chiara Vanetta5
1Department of Internal Medicine Cantonal Hospital of Baden Baden Switzerland.
Journal of the American Heart Association
|December 14, 2024
概括
定期饮用咖啡可能有利于心房动的老年人的认知功能. 更高的摄入量与更好的认知评分和减少的炎症标志物相关,表明有保护作用.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 营养科学 营养科学
背景情况:
- 心房动是认知障碍的一个已知的危险因素.
- 咖啡消费在健康个体中提供认知益处,但其对心房动患者的影响仍在争论中.
- 这项研究研究了定期喝咖啡对老年患者认知衰退的影响,这些老年患者被诊断为心房动.
研究的目的:
- 为了检查定期咖啡消费与心房动的老年人认知表现之间的关联.
- 在这个患者群体中探索咖啡摄入量和炎症标志物之间的关系.
- 为了确定咖啡消费是否可以减轻弱势群体的认知衰退.
主要方法:
- 认知功能使用综合的神经认知测试电池进行评估,包括蒙特利尔认知评估,Trail-Making测试,语义流性和数字符号替换测试.
- 每日咖啡消费量通过结构化营养问卷量化.
- 测量了炎症标志物,高灵敏度C反应蛋白 (hs-CRP) 和介白素-6 (IL-6). 线性混合效应模型用于数据分析,控制潜在的混因素.
主要成果:
- 与较低摄入量 (<1杯/天) (p=0.048) 相比,较高的咖啡消费 (每天超过5杯) 与显著改善的认知构造得分相关 (p=0.048).
- 虽然蒙特利尔认知评估得分显示咖啡摄入量增加的积极趋势,但差异在统计学上并不显著 (p=0.163).
- 炎症标志物,特别是IL-6,随着咖啡消费的增加显著下降 (p=0.017),而hs-CRP显示出非显著的下降趋势.
结论:
- 患有心房的患者的咖啡消费可能与增强的认知表现有关.
- 在这一群体中,较高的咖啡摄入量似乎与减少的全身炎症有关.
- 需要进一步的研究来验证这些发现,并探索咖啡在心房管理的饮食建议中的潜在作用.
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