身体尺寸和职业身体活动在生命过程中和胃肠道癌症
Michele Sassano1, Mahdi Nalini2, Monireh Sadat Seyyedsalehi1,3
1Department of Medical and Surgical Sciences, University of Bologna, JapanBolognaJapan, Italy.
American journal of epidemiology
|December 14, 2024
概括
生活过程 身体大小和体力活动影响胃肠道癌症风险. 肥胖的时间影响风险,而职业体育活动与结肠癌有关.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 生活过程中体型,职业体力活动 (PA) 和胃肠道 (GI) 癌症之间的关联仍然不清楚.
- 了解这些关系对于癌症预防策略至关重要.
研究的目的:
- 调查体型和职业PA在不同生命阶段对肠胃癌发病率的影响.
- 确定超重/肥胖的时间是否会影响特定的胃肠道癌症风险.
主要方法:
- 分析了来自戈勒斯坦队列研究的数据,这是一组前性队列,包括50 045名年龄在40-75岁的伊朗成年人.
- 在青春期,早期成年期和基线时使用经过验证的图标来评估身体尺寸.
- 在青春期和基线评估职业PA水平.
主要成果:
- 青少年体型较大与整体胃肠道癌和肝癌有关.
- 大的早期成年人体大小与肝癌有关.
- 青春期或早期成年期的超重/肥胖与胃,食道状细胞癌和肝癌有关.
- 较低的青少年职业PA与结肠癌相关;较低的基线PA与结肠癌相关,与直肠癌相反.
结论:
- 在生命过程中肥胖的时间可能会对各种胃肠道癌症的风险产生不同的影响.
- 职业体力活动主要与结肠癌风险有关.
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