小脑对情绪调节的贡献及其与中间前端GABA水平的关联
Yumi Oboshi1,2, Toshiki Iwabuchi3,4, Yohei Takata5
1Biofunctional Imaging Laboratory, Division of Preeminent Bioimaging Research, Institute of Photonics Medicine, Hamamatsu University School of Medicine, Chuo-ku, Hamamatsu 431-3192, Japan.
为了调节情绪,保持距离显示了对负面与积极刺激的独特大脑活动. 在负面情绪上调期间小脑活动的增加与中间前额叶皮层的GABA水平相关.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 情绪调节 情绪调节
背景情况:
- 隔离是一种通过改变心理距离来调节情绪的认知策略.
- 中间前额皮层 (MPFC) 是情绪调节的关键区域.
- 了解基于价值的情绪上调的神经差异至关重要.
研究的目的:
- 通过将正面和负面刺激之间的距离来研究情绪上调的神经差异.
- 探索中部前额叶皮层 (MPFC) 马胺黄油酸 (GABA) 度和情绪上调期间大脑活动之间的相关性.
主要方法:
- 使用磁共振光谱 (MRS) 和功能磁共振成像 (fMRI).
- 在34名健康的日本成年人中使用距离对情绪上调调的神经相关性进行了检查.
- 在MPFC中测量了马胺黄油酸 (GABA) 度.
主要成果:
- 与正面情绪上调相比,负面情绪上调显示了MPFC,左侧关节,双边前侧胰岛,前补充运动区域和双边小脑的激活增加.
- 在比较积极情绪上调与负面情绪上调时,没有发现显著的激活差异.
- 在负面情绪上调期间的右小脑活动与MPFC的GABA度正相关.
结论:
- 通过隔离来调节负面情绪的上调,与正面情绪的上调相比,涉及不同的神经通路.
- 小脑在通过距离来调节负面情绪方面发挥着作用.
- 前额前部GABA度与负面情绪调节期间的小脑活动有关.
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