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Updated: Jun 5, 2025

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在BRCA1卷轴-卷轴域中,林变异破坏了对PALB2的折叠和结合

Chrissy N S Baker1, Precious Grace C Pajela1, Davis E Martin1

  • 1Department of Biology, Texas Christian University, Fort Worth, Texas, USA.

Protein science : a publication of the Protein Society
|December 14, 2024
PubMed
概括

在BRCA1和PALB2基因中遗传突变会增加癌症风险. 一种新的测定有助于分类影响蛋白质结合的未知变异,改善了乳腺和卵巢癌的风险评估.

关键词:
这就是BRCA1的原因.在PALB2中,PALB2是PALB2.一个圆形的二重化.卷曲-卷曲的域名.异热定位热量计 异热定位热量计蛋白质蛋白质相互作用不知重要性的变体.

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