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对用于根管道堵塞的光固化水凝的评估

S Bhandari¹, S Kuehne², J Camilleri¹

¹Dentistry, School of Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.

Journal of dental research

|December 14, 2024

概括

一种新的光可治愈的根管填充材料,OdneFill,显示了与现有的密封剂相比较的物理特性,并增强了对多种生物膜的抗微生物活性,这表明它有可能用于内牙治疗.

科学领域:

牙周内科医院牙周内科医院牙周内科医院
牙科材料科学牙科材料科学

背景情况:

根通道堵塞的目的是消除残留的细菌,但再感染可能导致治疗失败.
目前使用gutta-percha和密封剂的方法需要精确的道准备.
一种新型的可光固化注射材料为根管填充提供了潜在的替代方案.

研究的目的:

描述一种新的光可治愈的注射性根管填充材料OdneFill的物理,化学和抗菌性质.
将OdneFill与已建立的根管密封剂 (AH Plus,BioRoot RCS) 进行比较.

主要方法:

用SEM,能量分散光谱学分析材料,并对流量,薄膜厚度,放射性透明度,溶解度和接触角度进行评估.
对多种生物膜和细菌酶 (脂酶,胆固醇化酶) 的抗微生物特性进行了评估.
使用活体/死体染色,共聚焦显微镜和体重变化分析量化了细菌活力和材料降解.

主要成果:

具有氧化填充剂的有机矩阵OdneFill显示了与AH Plus和BioRoot RCS相似的物理性能.
当暴露于常见的灌溶液和细菌酶时,该材料是稳定的.
与AH Plus相比,OdneFill对多种生物膜表现出优越的抗菌特性.

结论:

奥德尼菲尔为根运河堵塞提供了有利的物理和化学稳定性.
该材料具有增强的抗微生物疗效,使其成为内牙科应用的有希望的候选者.
需要进一步的临床研究来验证OdneFill在体内的性能.

关键词:

抗微生物药物是一种抗菌药物.材料表征材料的表征.微生物挑战微生物挑战堵塞退化退化密封者密封者密封者

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