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Updated: Jun 12, 2026

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
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使用细胞外近距离标记研究秘密相互作用的协议

Joshua A Rich1, Sadeechya Gurung1, Sasha Coates-Park1

  • 1Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

STAR protocols
|December 14, 2024
PubMed
概括

这项研究引入了一种新的方法,用于通过近距离结合来识别细胞外的蛋白质相互作用. 该协议有助于研究人员了解分泌蛋白质的细胞外相互作用.

关键词:
生物技术和生物工程细胞生物学 细胞生物学质谱测量质量谱测量蛋白质组学是指蛋白质组学.

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相关概念视频

Imperfections in Crystal Structure: Stoichiometric Point Defects01:26

Imperfections in Crystal Structure: Stoichiometric Point Defects

Schottky defects arise when some lattice points in a crystal, such as those in NaCl, remain unoccupied, creating lattice vacancies without disturbing the overall electrical neutrality of the crystal. This defect is common in ionic crystals where the positive and negative ions are similar in size, as seen in sodium chloride and cesium chloride. The presence of Schottky defects enables the crystal to conduct electricity to a small extent through an ionic mechanism. Electric fields cause nearby...