怀孕期间的COVID-19感染是否会导致先天性听力损失的风险?
Jane Sheehan1, Alison Jagger1, Kate L Francis2
1Centre for Community Child Health, The Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, Parkville, Victoria, Australia.
International journal of pediatric otorhinolaryngology
|December 14, 2024
概括
怀孕期间的COVID-19感染并没有增加婴儿患先天性听力损失的风险. 这项大型研究发现,新生儿听力检查结果或诊断出COVID-19或没有COVID-19的母亲产生的婴儿之间的听力损失没有差异.
科学领域:
- 产科和妇科 产科和妇科
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
背景情况:
- 孕期感染可能会导致先天性听力损失.
- 怀孕期间的COVID-19感染是对婴儿健康结果的担忧.
研究的目的:
- 调查孕妇怀孕期间COVID-19感染与婴儿先天性听力损失风险之间的关联.
- 分析与父母COVID-19状态有关的新生儿听力查和听力学诊断结果.
主要方法:
- 澳大利亚维多利亚州一项全民新生儿听力查计划的回顾性临床审计 (n=75,330名2022年出生的婴儿).
- 通过怀孕期间COVID-19感染的自我报告收集的数据.
- 使用双项分布的一般线性回归模型进行统计分析,以比较感染和非感染群体之间的结果.
主要成果:
- 在感染组 (1.4%) 和非感染组 (1.3%) 之间,婴儿被转诊诊断听力学的比例没有显著差异.
- 在两组中,被诊断患有任何类型和程度的听力损失的婴儿比例相似 (两组均为0.6%).
- 两组之间,母亲和婴儿的特征是可比的.
结论:
- 怀孕期间母亲的COVID-19感染与婴儿先天性听力损失的风险增加无关.
- 研究结果不支持在怀孕期间患有COVID-19的母亲产生的婴儿新生儿听力查的特定管理协议.
- 这项大规模的流行病学研究提供了关于怀孕安全性的强有力的证据,涉及COVID-19感染后婴儿听力结果.
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