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身体活动与周围动脉疾病患者的长期死亡率的关联:基于人口的队列研究

Jianping Xiong¹, Qichen Feng¹, Shilu Zhao¹

¹Department of Interventional Radiology and Vascular Surgery, Peking University Third Hospital, Beijing, China.

Annals of vascular surgery

|December 14, 2024

概括

定期有氧活动显著降低了周围动脉疾病 (PAD) 患者的死亡风险. 肌肉强化炼也为PAD的心血管疾病 (CVD) 死亡率提供了生存益处.

科学领域:

心脏病学心脏病学
公共卫生公共卫生
运动科学运动科学

背景情况:

周围动脉疾病 (PAD) 是心血管疾病 (CVD) 和全因死亡率的重要风险因素.
了解体育活动对PAD患者死亡风险的影响对于开发有效干预措施至关重要.

研究的目的:

调查PAD诊断的患者体力活动与所有原因和心血管疾病死亡率的风险之间的关联.
确定可降低该人口死亡风险的特定类型和体育活动量.

主要方法:

利用了在国家健康和营养检查调查 (1999-2004) 中招募的561名PAD患者的数据.
连接到2019年12月31日的死亡率数据,分析平均9.8年的随访结果.
采用Cox比例危险模型来评估有氧和肌肉强化活动对死亡风险的影响.

主要成果:

在随访期间,在561名PAD患者中,共记录了435例死亡 (165例心血管疾病死亡).
每周至少60分钟进行中度至强度有氧体力活动 (MVPA) 与45%较低的全因死亡风险和60%较低的心血管疾病死亡风险有关.
每周1-4次的肌肉增强活动与66%的心血管疾病死亡风险降低有关. 在每周120-239分钟的MVPA时,观察到最大的生存益处.

结论:

有氧体力活动,特别是MVPA≥60分钟/周,在PAD患者中显著降低所有原因和心血管疾病死亡率.
肌肉增强活动,每周进行1-4次,也可以通过降低PAD患者心血管疾病死亡风险,有助于改善生存率.

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