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通过体外深度突变扫描方法和其应用程序进行皮层图谱绘制

Meredith M Keen1, Alasdair D Keith1, Eric A Ortlund1

  • 1Department of Biochemistry, Emory School of Medicine, Emory University, Atlanta, Georgia, USA.

The Journal of biological chemistry
|December 14, 2024
PubMed
概括

深度突变扫描 (DMS) 为表位图绘制提供了一种高通量,高分辨率的方法,克服了传统技术的局限性. 这种方法加速了免疫疗法,诊断和疫苗的开发.

关键词:
抗体工程是针对抗体的工程.深度突变扫描 (deep mutational scanning) 是一种对突变进行深度扫描的方法.诊断 诊断 诊断 诊断 诊断标本地图绘制 标本地图绘制免疫疗法 免疫疗法将基因型与表型联系起来.疫苗的设计是如何设计的病毒监测 病毒监测

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