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Updated: Jun 5, 2025

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
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A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

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针对初级和二级中枢神经系统淋巴瘤的抗CD19CAR T细胞疗法

Giulia Losi1,2, Alberto Mussetti3, Marta Peña3

  • 1Clinical Hematology Department, Institut Català d'Oncologia-L' Hospitalet, IDIBELL, Barcelona, Spain. giulia.losi09@gmail.com.

Bone marrow transplantation
|December 14, 2024
PubMed
概括

中枢神经系统淋巴瘤 (CNSL) 是一种具有侵略性的瘤,在复发时治疗选择有限. 抗CD19CAR-T细胞疗法显示为对这些具有挑战性的中枢神经系统淋巴瘤病例的新治疗途径具有前途.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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