公众对医学创新的研发贡献:一个分析框架
Claudia Wild1, Ozren Sehic1, Louise Schmidt1
1Austrian Institute for Health Technology Assessment (AIHTA), Vienna, Austria.
公共资金显著支持药物开发,超过一半的批准药物和90%的药物目标与公共机构有关. 标准化报告对于研发投资的透明度至关重要.
科学领域:
- 制药研发领域的研发工作.
- 卫生经济学 卫生经济学
- 公共政策 公共政策
背景情况:
- 欧盟制药立法第57条要求披露直接的公共研发资金.
- 目前的报告缺乏标准化的方法来记录直接和间接的公共捐款.
- 在定义"直接"与"间接"公共研发支持方面存在模糊性.
研究的目的:
- 确定向R&D提供直接和间接公共贡献的报告类别.
- 制定一个标准化报告公共研发资金的框架.
- 澄清"直接"和"间接"公共捐款的解释.
主要方法:
- 代的混合方法方法,结合文献综述和利益相关者采访.
- 针对性地在文献中搜索有关公共研发贡献的初级数据.
- 确定用于研发投资分析的相关数据源.
主要成果:
- 分析了26篇出版物,揭示了公共部门在药物开发中的重大参与.
- 50%的批准药物和90%以上的药物目标来自公共机构或其分支机构.
- 在整个研发价值链中确定了八个类别的公共贡献,从基础研究到市场后监督.
结论:
- 提出了一个结构化的框架,用于确定对医疗产品开发的公共和慈善贡献.
- 目前关于研发贡献的文档往往不完整.
- 调整公共政策,促进对研发投资的透明和详细报告至关重要.
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