影响孤儿药物的出现因素的相互关系动态
Rinchen Gensapa1, Vivek Pandey1, Saibal Kumar Saha2
1Sikkim Manipal Institute of Technology, Sikkim Manipal University, Majitar, East Sikkim, India.
Annales pharmaceutiques francaises
|December 15, 2024
概括
政府政策,互联网技术和财政激励是增加孤儿药物可用性的关键驱动力. 这些因素,以及患者的支持,鼓励药物开发用于罕见疾病.
科学领域:
- 药物经济学 药物经济学
- 卫生政策 卫生政策
- 生物技术是生物技术.
背景情况:
- 针对罕见疾病开发的孤儿药物,由于患者人数较少和高的研发成本而面临挑战.
- 制药公司往往缺乏投资孤儿药制造的激励,导致有限的可用性.
- 政府的立法和激励措施对于鼓励孤儿药物开发和可访问性至关重要.
研究的目的:
- 探索影响孤儿药物的可用性增加的因素之间的相互关系.
- 确定推动孤儿药物发展和近期药物获取的因果关系因素.
主要方法:
- 一项涉及38名专家的研究进行了分析十个关键因素.
- 使用决策试验和评估实验室 (DEMATEL) 技术进行分析.
- 分析的因素包括互联网技术,立法,患者支持小组,政府子公司,生物技术进步,企业社会责任,疾病意识/诊断和制药预算.
主要成果:
- 信息技术,立法,患者支持小组和专门的预算被确定为因果因素.
- 疾病意识,诊断,药物可用性,政府子公司,企业社会责任和生物技术成为影响因素.
- 这些发现突出了影响孤儿药物可用性的复杂相互作用.
结论:
- 支持性立法的战略实施,技术整合和财务承诺对于孤儿药物开发至关重要.
- 提高疾病意识和诊断能力进一步刺激了罕见疾病治疗的市场.
- 涉及政策,技术和行业投资的多方面的方法对于改善获得孤儿药物的机会至关重要.
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