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奥诺德拉的预后营养在预测舌头状细胞癌的预后的有效性

Satoshi Fukuzawa¹, Kenji Yamagata¹, Ryo Takasaki¹

¹Oral and Maxillofacial Surgery, Department of Clinical Medicine, Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

Journal of stomatology, oral and maxillofacial surgery

|December 15, 2024

概括

手术前的营养评估,特别是奥诺德拉的预后营养指数 (OPNI),可以预测舌头癌症的预后. 这一指数与身体质量指数 (BMI) 一起显示,在患有舌头状细胞癌的患者中,与整体存活率有显著的关联.

科学领域:

在瘤学瘤学.
营养科学营养科学
手术预后手术预后

背景情况:

舌状细胞癌 (TSCC) 的预后受到各种因素的影响.
手术前的营养状况越来越被认为是患者结果的关键决定因素.
确定可靠的预后标志物对于优化TSCC治疗策略至关重要.

研究的目的:

评估手术前营养标志物对TSCC患者的生存率的影响.
确定各种营养指数的预测值,包括OPNI和PINI,用于总生存期 (OS) 和无病生存期 (DFS).

主要方法:

一项对126名TSCC患者进行彻底手术的回顾性队列研究.
进行手术前血液标志物的分析,包括GGT,CAR,GLR,GPR,GNR,NLR,PLR,OPNI,PINI和白蛋白.
使用单变量和考克斯回归分析评估OS和DFS.

主要成果:

单变量分析确定了入侵深度,阶段,BMI,OPNI,PINI和白蛋白作为OS的显著预测因素.
考克斯回归证实BMI,病理等级和OPNI是显著的预后因素.
截止值为51.05的OPNI证明了其在预测TSCC预后方面的有效性.

结论:

奥诺德拉的预后营养指数 (OPNI) 是舌头癌症的一个有价值的预后因素.
术前营养评估,特别是OPNI和BMI,可以帮助预测TSCC患者的结果.

关键词:

一个人的预后营养指数 (OPNI)口腔状细胞癌 (OSCC) 是一种预测营养指数 (PNI) 是指预测营养指数.舌头状细胞癌瘤

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