慢性移植对宿主疾病对儿童和年轻成年人的学校成绩产生不利影响
Zahra Hudda1, Amanda Flannery2, Patricia Dillhoff3
1Division of Bone Marrow Transplant and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.
慢性移植与宿主疾病 (cGVHD) 显著影响儿童的学校经验,导致学业延迟和社会情感挑战. 这些儿科幸存者的早期学校干预是必要的.
科学领域:
- 儿科血液学/瘤学
- 儿童癌症幸存率 儿童癌症幸存率
- 异构血造干细胞移植 (HSCT) 的方法
背景情况:
- 慢性移植对宿主疾病 (cGVHD) 影响成年HSCT幸存者恢复工作.
- 缺乏关于cGVHD对儿科HSCT幸存者的学校再融入的影响的数据.
- 这项研究调查了cGVHD对HSCT后儿童学校经验的影响.
研究的目的:
- 为了确定cGVHD是否对儿科HSCT幸存者的学校经历产生不利影响.
- 为了比较学业成绩和社会情感方面的学校教育的孩子和没有cGVHD.
主要方法:
- 进行了一项单中心,横截面试验研究.
- 一个由42个项目组成的问卷评估了HSCT前后的学术和社会情感学校教育方面.
- 40名学龄儿童HSCT患者 (20名cGVHD,20名对照) 填写了调查问卷.
主要成果:
- 20名cGVHD患者中有10人经历学术延迟;2人无法恢复上学.
- 所有对照患者恢复上学;cGVHD患者有慢性缺勤 (≥4天/月).
- cGVHD患者面临的障碍 (外观,舒适) 和缺乏学校住宿 (只有33%的人得到了).
结论:
- 儿童cGVHD幸存者在学校面临着深刻的学术,情感和心理社会挑战.
- 对于这些孩子的学校服务和住宿,存在很大的差距.
- 未来的研究应该评估为儿童cGVHD幸存者提供标准化的,基于学校的早期干预措施.
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