系统性抗生素预防 辅助手术重建性周植入炎治疗:一项回顾性研究
Ausra Ramanauskaite1, Ioanna Saltzer1, Ninad Padhye1
1Department of Oral Surgery and Implantology, Goethe-University Frankfurt, Carolinum, Frankfurt, Germany.
Clinical implant dentistry and related research
|December 15, 2024
概括
系统性抗生素预防并没有显著改善外科围植入炎治疗的结果. 临床结果,包括探测深度和探测出血,在没有服用抗生素,术前抗生素或术后抗生素的组之间是相似的.
科学领域:
- 牙科植入物学 牙科植入物学
- 牙周病学 牙周病学
- 在口腔外科手术.
背景情况:
- 牙周植入物炎是植入牙植入物放置后的一个普遍并发症.
- 手术重建性治疗旨在管理植入周炎,但其疗效可能受到辅助疗法的影响.
- 系统性抗生素预防在改善围植入炎外科手术结果中的作用仍在争论中.
研究的目的:
- 评估系统性抗生素预防的临床疗效,当与外置植入炎外科重建治疗一起使用时.
- 为了比较没有接受抗生素,术前抗生素和术后抗生素的患者之间的结果.
主要方法:
- 一项前性研究涉及49名患有围植入炎的患者 (70个植入物) 接受手术治疗.
- 患者被分为三个组:没有全身抗生素 (No-Ab),一次性手术前剂量 (手术前) 或阿莫西西林的3天术后疗程 (手术后).
- 临床参数包括探测深度 (PD),探测出血 (BOP),斑块指数 (PI),度 (Sup) 和最大PD在基线,6个月和12个月被评估.
主要成果:
- 经过12个月,所有组的平均PD减轻值都相似 (在No-Ab中为-1.74毫米,在手术前为-1.91毫米,在手术后为-1.13毫米),没有统计学上显著的差异.
- 在没有Ab,手术前和手术后组中,BOP,PI,Sup和最大PD的减少也相似.
- 在12个月内,疾病的治愈率为61.5% (No-Ab),73.7% (手术前) 和89.5% (手术后),两组之间没有显著差异.
结论:
- 系统性抗生素预防,无论是术前还是术后,都没有证明手术重建性围植入炎治疗的临床结果有显著改善.
- 这些发现表明,辅助性全身抗生素可能不必在这种治疗背景下取得有利结果.
- 进一步的研究可以探索特定的患者亚组或替代抗生素治疗方案.
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