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Updated: Jun 5, 2025

Efficient Transcriptionally Controlled Plasmid Expression System for Investigation of the Stability of mRNA Transcripts in Primary Alveolar Epithelial Cells
10:49

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Published on: March 6, 2020

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代谢基因的JUNB O-GlcNAcylation-Mediated Promoter可访问性在肺纤维化中调节了明显的上皮细胞系

Marie-Therese Bammert1,2, Meshal Ansari3, Leoni Haag1

  • 1Lung Repair & Regeneration Department, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400, Biberach, Germany.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|December 16, 2024
PubMed
概括

研究人员在异常性肺纤维化 (IPF) 中发现了一种新的机制,涉及代谢变化和基因调节. 针对O-GlcNAc-JUNB通路可能为这种致命的肺部疾病提供新的治疗方法.

关键词:
在JUNB中,JUNB是指JUNB的意思.这是一种O-GlcNAcylation.异常的上皮细胞重塑.支气管的支气管化肺部纤维化 肺部纤维化

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A Mimic of the Tumor Microenvironment: A Simple Method for Generating Enriched Cell Populations and Investigating Intercellular Communication09:52

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