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超重和肥胖儿童的慢性炎症标记:一个横截面分析研究

Rajasekar Gokulakrishnan¹, Chinnaiah G Delhikumar¹, Gandhipuram P Senthilkumar²

¹Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Indian journal of endocrinology and metabolism

|December 16, 2024

概括

这项研究发现,肥胖儿童和正常儿童之间的炎症标志物没有显著差异. 然而,肥胖儿童经常经历诸如失脂症和胰岛素抵抗等并发症.

科学领域:

儿科儿科儿科
免疫学免疫学免疫学
代谢障碍代谢障碍代谢障碍

背景情况:

儿童肥胖与慢性低度系统性炎症有关.
这种炎症会导致各种与肥胖相关的健康问题 (并发症).

研究的目的:

为了比较肥胖和正常儿童之间的炎症标志物.
评估儿童中与肥胖相关的并发病的患病率.

主要方法:

一项涉及40名肥胖儿童和40名年龄/性别匹配的正常儿童的横截面研究.
测量的炎症标志物:hs-CRP,IL-6,IL-10和脂肪蛋白.
对并发症进行查:甲状腺功能低下,脂质失调,胰岛素抵抗,高血压和NAFLD.

主要成果:

在肥胖儿童和正常儿童之间,在hs-CRP,IL-6,IL-10或阿迪波内克丁水平上没有发现显著差异.
脱脂症 (80%) 和胰岛素抵抗 (52.5%) 是肥胖儿童中最常见的并发症.
介乐-6与总胆固醇,LDL和HDL水平呈正相关性.

结论:

在这个队列中,肥胖儿童和正常儿童之间的炎症标志物没有显著差异.
脱脂症和胰岛素抵抗是与儿童肥胖相关的常见健康问题.

关键词:

孩子孩子孩子孩子伴随性疾病的发生.炎症标志物炎症标志物肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖

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